Sigma-Aldrich Silica Gel 60 2 Mm 12 Plc

Material

glass support
silica gel 60 matrix

Quality Level

100

Feature

binder Organic Polymer
fluorescent indicator: no

Packaging

pkg of 12 plates

Technique(S)

thin layer chromatography (TLC): suitable

Layer Thickness

2 mm

Plate L × W

20 cm × 20 cm

Particle Size

20-40 μm

Pore Size

60 Å medium pore diameter

Storage Temp.

2-30°C

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Thin Layer Chromatography (TLC)

General Description

12 Glass plates 20 x 20 cmPLC plates allow users to separate samples that vary greatly in size – from grams down to milligrams. Available with or without a fluorescence indicator, PLC plates has 2 mm thickness. They also use our same proven silica-binder technology as in analytical TLC plates. To isolate the substance by extraction, users can simply scrape the spot from the layer.

Application

• Stability indicating high performance thin layer chromatography method development and validation for quantitative determination of tetracycline hydrochloride: This paper describes the use of Silica gel 60, 2 mm TLC plates to develop a robust method for the quantitative analysis of tetracycline hydrochloride in pharmaceutical forms, enhancing drug stability and quality monitoring (Gashaw et al., 2024).
• Ecofriendly single-step HPLC and TLC methods for concurrent analysis of ternary antifungal mixture in pharmaceutical products: Highlighting the application of Silica gel 60, 2 mm plates in the simultaneous determination of antifungal agents, this research contributes to the quality control of pharmaceuticals through innovative chromatographic techniques (Abdelrahman et al., 2023).
• Simultaneous analysis of levamisole with triclabendazole in pharmaceuticals through developing TLC and HPLC-PDA chromatographic techniques: This study demonstrates the use of Silica gel 60, 2 mm plates for simultaneous drug analysis, supporting enhanced pharmaceutical analysis and regulatory compliance (Attia et al., 2023).
• Identification of variety-specific metabolites of basil by high performance thin layer chromatography-assisted metabolic profiling techniques: Utilizing Silica gel 60, 2 mm plates, this research identifies specific metabolites in basil, showcasing the plates′ utility in botanical studies and ingredient verification (Wulandari et al., 2023).

Linkage

Replaces: 5745-7; 5745

Analysis Note

Layer thickness: 1700 - 2100 µm
Deviation of layer thickness per plate: ≤ 300 µm
Chromatographic testing:
colour test
hRf-values
- bleu vif organol, colour test, lipophile:
25 - 35
- Ceres Black G, colour test, lipophile: 50 - 60
- ceres Violet brn, colour test, lipophile: 65 - 80
Typical value determined on a conditioned plate
Eluent: toluene (45% rel. humidity)