Sigma-Aldrich Isatin 97%

List Price $38.22 Your Price $38.22
Sigma-Aldrich Isatin 97% - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-114618-5G
MFG.PART: 114618-5G
UNSPSC: 12352100
Manufacturer: Sigma-Aldrich

Quality Level

100

assay

97%

form

powder

mp

193-195 °C (dec.) (lit.)

solubility

boiling water: soluble
diethyl ether: soluble
soluble

SMILES string

O=C1Nc2ccccc2C1=O

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)

InChI key

JXDYKVIHCLTXOP-UHFFFAOYSA-N

Related Categories

Heterocyclic Building Blocks

Application

Isatin can be used as a reactant to prepare:
  • Phthalazinone derivatives.[1]
  • Spirooxindole derivatives.[2]
  • Agents against multidrug-resistant cells expressing P-glycoprotein.[3]
  • Thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B.[4]
  • Triazole-isatine compounds as potential antibacterial and antifungal agents.[5]
  • Biologically relevant scaffolds such as spiro[indole-thiazolidinones].[6]

It can be a reactant for:
  • Cascade reactions with heterocyclic ketene aminals.[7]
  • Knoevenagel condensation reactions.[8]

Isatin can also be used as a chromatographic spray reagent for amino acids, and also as a reference material in the preparation of indigo and Maya Blue. It is responsible for the yellow color exhibited by the "Maya Yellow" pigment.[9]
Isatin undergoes Pd(II)-catalyzed C-H addition by direct sp2/sp3 C-H bond activation to form 3-substituted-3-hydroxy-2-oxindoles[10]. Isatin derivatives (bis-Schiff base) are synthesized by the condensation of the natural or synthetic isatins with hydrazine[11].

wgk_germany

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

More Information
SKU SIAL-114618-5G
Featured No
Supplier Part Number 114618-5G
UM EA
UNSPSC 12352100
Manufacturer Name Sigma-Aldrich
Temperature room temp
Refrigerated-Frozen N
ProductLine SIAL
Qty 1
MinOrderQty 1
Weight 10.000000
Lead Time 9
Hazardous N
CAS Number 91-56-5
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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