Sigma-Aldrich 2-Biotinyldimedone Novabio

Quality Level

200

Product Line

Novabiochem^®

Assay

≥98% (TLC)
≥98.0% (HPLC)

Form

powder

Reaction Suitability

reaction type: Biotinylations

Manufacturer/Tradename

Novabiochem^®

Application(S)

peptide synthesis

Storage Temp.

2-30°C

Related Categories

Amino Acids, Resins & Reagents for Peptide Synthesis

General Description

A reagent for the reversible labeling of peptides with biotin . Labeling of the N-terminal amine of resin-bound peptides is carried out by incubating overnight with excess reagent in DMF. The biotinylated peptide is obtained following TFA cleavage. Removal of the biotin label is effected by treatment with 5% aqueous hydrazine.

Associated Protocols and Technical Articles
Purification of Peptides using Chemoselective Tags

Literature references

B. Kellam, et al. (1997)Tetrahedron Lett.,38, 5391

Linkage

Replaces: 01-63-0108

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^®products please click here.Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany