GenScript Tnf-Α, Rat; 1mg

List Price $1,105.00 Your Price $1,105.00
GenScript Tnf-Α, Rat - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z02999-1
MFG.PART: Z02999-1
UNSPSC: 41106514
Manufacturer: GenScript USA Inc
Product Introduction
Species Rat
Protein Construction

Expressed with an N-terminal Met.

TNF-α (Leu80-Leu235)
Accession # P06804
Purity > 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
Biological Activity ED50 < 50.0 pg/ml, measured in a cytotoxicity assay using mouse L-929 cells in the presence of actinomycin D, corresponding to a specific activity of > 2.0 × 107 units/mg.
Expression System P. pastoris
Apparent Molecular Weight ~17.4 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

Background
Target Background Tumor Necrosis Factor-Alpha (TNF-alpha) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune disease. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune disease including Crohns disease, rheumatoid arthritis and graft-versus-host disease. TNF alpha-1a is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Synonyms TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; DIF; TNFA; TNFSF2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


More Information
SKU GSCRPT-Z02999-1
Featured No
Supplier Part Number Z02999-1
UM EA
UNSPSC 41106514
Manufacturer Name GenScript USA Inc
Temperature Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (examp
ProductLine GSCRPT
Qty 1
MinOrderQty 1
Weight 7.000000
Lead Time 7
Hazardous N
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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