Cell Signaling Tra-1-60(S) (Tra-1-60(S)) Mouse mAb

Name: Cell Signaling Tra-1-60(S) (Tra-1-60(S)) Mouse mAb
SKU: CSIG-4746T
Price: 144.43 USD

List Price $144.43 Your Price $144.43

Cell Signaling Tra-1-60(S) (Tra-1-60(S)) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-4746T

MFG.PART: 4746T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	20 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	200-400
Source/Isotype	Mouse IgM
Application/Dilution	{Western Blotting: 1:1000, Immunohistochemistry (Paraffin): 1:100, Immunofluorescence (Immunocytochemistry): 1:1000, Flow Cytometry (Fixed/Permeabilized): 1:400, Flow Cytometry (Live): 1:400}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	TRA-1-60(S) (TRA-1-60(S)) Mouse mAb detects endogenous levels of the neuraminidase-sensitive TRA-1-60 antigen.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with human embryonic carcinoma 2102Ep cl.2A6 cells.
Background	TRA-1-60 and TRA-1-81 antibodies detect antigens present on the surface of human stem, teratocarcinoma, and embryonic germ cells (1). TRA-1-60(S) reacts with a neuraminidase sensitive epitope of a proteoglycan (2,3), while TRA-1-81 reacts with a neuraminidase insensitive epitope on the same antigen. Recently this antigen has been proposed to be a form of the protein podocalyxin (4). TRA-1-60 is also detected in the serum of patients with germ cell tumors (5,6).

Specifications