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Cell Signaling Cd11c (3.9) Mouse mAb (Apc Conjugate)
List Price
$278.76
Your Price
$278.76
Cell Signaling Cd11c (3.9) Mouse mAb (Apc Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
NETA PART:
CSIG-36268S
MFG.PART:
36268S
UNSPSC:
12352203
Manufacturer:
Cell Signaling
| Size | 500 µl (100 tests) |
| Reactivity | H |
| Sensitivity | Endogenous |
| Source/Isotype | Mouse IgG1 |
| Application/Dilution | {Flow Cytometry (Fixed/Permeabilized): 1:20, Flow Cytometry (Live): 1:20} |
| Storage | Supplied in 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2. This product is stable for 12 months when stored at 4ºC. Do not aliquot the antibody. Protect from light. Do not freeze. |
| Specificity/Sensitivity | CD11c (3.9) Mouse mAb (APC Conjugate) recognizes endogenous levels of total CD11c protein. This antibody detects an epitope within the extracellular domain. |
| Species Reactivity | Human |
| Source/Purification | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. |
| Background | CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins (1). CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production (2, 3). CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia (4-7).The 3.9 antibody is widely used as a marker for CD11c expression on the above mentioned cell types. |
| SKU | CSIG-36268S |
|---|---|
| Featured | No |
| Supplier Part Number | 36268S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer Name | Cell Signaling |
| MSDS URL | Click here |
| Temperature | +4C |
| CountryOfOrigin | United States |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| ACT Ecolabel | No |