Cell Signaling Alpha/Beta-Synuclein (Syn205) Mouse mAb

Name: Cell Signaling Alpha/Beta-Synuclein (Syn205) Mouse mAb
SKU: CSIG-2644T
Price: 144.43 USD

List Price $144.43 Your Price $144.43

Cell Signaling Alpha/Beta-Synuclein (Syn205) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-2644T

MFG.PART: 2644T

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	20 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	18
Source/Isotype	Mouse IgG1
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50, Immunohistochemistry (Paraffin): 1:100, Immunofluorescence (Frozen): 1:200}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	α/β-Synuclein (Syn205) Mouse mAb detects endogenous levels of total synuclein protein. α/β-Synuclein (Syn205) Mouse mAb detects recombinant α and β-synuclein (Giasson, B.I. et al., 2000).
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with human recombinant α- and β-synucleins and the epitope maps to the carboxy terminus of the protein.
Background	α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-Synuclein gene are linked to Parkinsons disease (1).

Specifications