GenScript Siglec-2/Cd22, Hfc, Human; 100ug

List Price $220.00 Your Price $220.00
GenScript Siglec-2/Cd22, Hfc, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART: GSCRPT-Z03643-100
MFG.PART: Z03643-100
UNSPSC: 12352202
Manufacturer: GenScript USA Inc
Product Introduction
Species Human
Protein Construction
Siglec-2/CD22 (Asp20-Arg687)
Accession # P20273
hFc
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Biological Activity Immobilized Human Siglec2 at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Anti-Siglec2 Ab with the EC50 of 0.2 μg/ml determined by ELISA.
Expression System Expi293
Apparent Molecular Weight 120~130 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. Normally 5 % trehalose is added as protectant before lyophilization.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles.


Background
Target Background CD22, or cluster of differentiation-22, is a molecule belonging to the SIGLEC family of lectins. It is found on the surface of mature B cells and to a lesser extent on some immature B cells. CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyers patches in mice.
Synonyms CD22 molecule; CD22; Siglec2; Siglec-2;B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; sialic acid binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2;  SIGLEC2FLJ22814; T-cell surface antigen Leu-14

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


More Information
SKU GSCRPT-Z03643-100
Featured No
Supplier Part Number Z03643-100
UM EA
UNSPSC 12352202
Manufacturer Name GenScript USA Inc
Temperature Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Avoid repeated freeze-thaw cycles.
ProductLine GSCRPT
Qty 1
MinOrderQty 1
Weight 7.000000
Lead Time 7
Hazardous N
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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