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GenScript Siglec-15 Fc Chimera, Human; 100 μg
List Price
$220.00
Your Price
$220.00
GenScript Siglec-15 Fc Chimera, Human - GSCRPT (Additional S&H or Hazmat Fees May Apply)
NETA PART:
GSCRPT-Z03571-100
MFG.PART:
Z03571-100
UNSPSC:
12352202
Manufacturer:
GenScript USA Inc
Product Introduction
| Species | Human | ||||
| Protein Construction |
| ||||
| Purity | > 90% as analyzed by SDS-PAGE | ||||
| Endotoxin Level | < 1 EU/μg of protein by gel clotting method | ||||
| Biological Activity | Immobilized Anti-Siglec15 at 1.0 μg/ml (100 μl/well) can bind Siglec-15, hFc, Human with a EC50 = 5.184 ng/ml and a linear range of 0.064−200.0 ng/ml when detected by Mouse Anti–Human IgG Fc-HRP. | ||||
| Expression System | HEK 293 | ||||
| Apparent Molecular Weight | ~54.3 kDa, on SDS-PAGE under reducing conditions. | ||||
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Background
| Target Background | Siglec-15 preferentially recognizes the Neu5Acalpha2-6GalNAcalpha- structure. Siglec-15 associates with the activating adaptor proteins DNAX activation protein (DAP)12 and DAP10 via its lysine residue in the transmembrane domain. Siglec-15 is the second human Siglec identified to have an activating signaling potential; unlike Siglec-14, however, it does not have an inhibitory counterpart. |
| Synonyms | CD33L3; HsT1361; SIGLEC-15 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
| SKU | GSCRPT-Z03571-100 |
|---|---|
| Featured | No |
| Supplier Part Number | Z03571-100 |
| UM | EA |
| UNSPSC | 12352202 |
| Manufacturer Name | GenScript USA Inc |
| Temperature | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (examp |
| ProductLine | GSCRPT |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 7 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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