The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Millipore This Anti-Myosin 2 Antibody, Clone 5b11.1 Is Validated For Use In Western Blotting, Ihc For The Detection Of Myosin 2. - Mill (Additional S&H or Hazmat Fees May Apply)
Myosin is a hexameric protein consisting of two heavy chains including Myosin-2 (MYH2), two regulatory light chains, and two alkali light chains. The myosin-2 heavy chain interacts with the actin cytoskeleton and mediates muscle contractility in eukaryotic cells. Defects in myosin-2 result in inclusion body myopathy type 3.
Product Information
Format
Purified
Control
Human cardiac muscle tissue
Presentation
Purified mouse monoclonal IgG3κ in buffer containing PBS with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-Myosin 2 Antibody, clone 5B11.1 is validated for use in Western Blotting, IHC for the detection of Myosin 2.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Western Blot Analysis: 0.5 µg/mL from a representative lot detected Myosin-2 in L6 cell lysate (Myosin may be observed as a smear in some cell lysates).
Western Blot Analysis: A representative lot detected Myosin-2 in mouse heart cell cytosolic extracts.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to mouse Myosin 2.
Clone
5B11.1
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Isotype
IgG3κ
Species Reactivity
Human
Mouse
Rat
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_060004
Gene Symbol
MYH2
MYHSA2
UniProt Number
Q9UKX2
Molecular Weight
~220 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Immunohistochemistry in human cardiac muscle tissue.
Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Myosin-2 in human cardiac muscle tissue.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
