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Millipore Detect Wave1 Using This Mouse Monoclonal Antibody, Anti-Wave-1 Antibody, Clone K91/36 Validated For Use In Western Blotting & Ihc. - Mill (Additional S&H or Hazmat Fees May Apply)
Protein WAVE-1 (WAVE1) is also known as Wiskott-Aldrich syndrome protein (WASP) family member 1 (WASF1), verprolin homology domain-containing protein 1, or SCAR1. WAVE1 is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1 binds actin and ARP2/3 complex. It binds the ARP2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain. WAVE1 is highly expressed in brain, with low expression in several other tissue.
Product Information
Format
Purified
Control
Rat brain tissue lysate
Presentation
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
Detect WAVE1 using this mouse monoclonal antibody, Anti-WAVE-1 Antibody, clone K91/36 validated for use in western blotting & IHC.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Immunohistochemistry Analysis: A representative lot detected WAVE-1 in adult rat hippocampal CA1 tissue (Prof. J. Trimmer, University of California, Davis).
Biological Information
Immunogen
Linear peptide corresponding to human WAVE-1.
Clone
K91/36
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Isotype
IgG1κ
Species Reactivity
Rat
Human
Mouse
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_001020105
Gene Symbol
WASF1
KIAA0269
SCAR1
WAVE1
Purification Method
Protein G Purified
UniProt Number
Q92558
Molecular Weight
~ 70 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected WAVE-1 in 10 µg of rat brain tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
