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Millipore This Anti-Ddpiv/Cd26 Antibody, Clone 9f1.2 Is Validated For Use In Western Blotting For The Detection Of Ddpiv/Cd26. - Mill (Additional S&H or Hazmat Fees May Apply)
Dipeptidyl peptidase 4 (EC 3.4.14.5; UniProt P27487; also known as ADABP, ADCP-2, Adenosine deaminase complexing protein 2, DPP IV, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, Dipeptidyl peptidase 4, Dipeptidylpeptidase IV, TP103) is encoded by the DPP4 (also known as CD26, ADCP2) gene (Gene ID 1803) in human. DPPIV is a homodimeric serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. It is involved in many cellular processes such as activation of cytokines, differentiation, and cell-matrix interactions. Inhibition of DPPIV has been reported to be an effective treatment for type II diabetes. Also, DPPIV acts as a functional receptor for the newly discovered Middle East respiratory syndrome (MERS) coronavirus.
Product Information
Format
Purified
Presentation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-DDPIV/CD26 Antibody, clone 9F1.2 is validated for use in Western Blotting for the detection of DDPIV/CD26.
Key Applications
Western Blotting
Biological Information
Immunogen
GST-tagged recombinant protein corresponding to the extracellular domain of human DDPIV/CD26.
Epitope
extracellular domain
Clone
9F1.2
Concentration
Please refer to lot specific datasheet.
Host
Mouse
Specificity
Reacts with both membrane-bound (MDPP) and soluble (SDPP) forms.
Isotype
IgG2aκ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NP_001926
Gene Symbol
DPP4
ADCP2
CD26
Purification Method
Protein G Purified
UniProt Number
P27487
Molecular Weight
~100 kDa observed. Due to glycosylation, target band appears larger than the calculated molecular weight of 88.3 (MDPP) & 84.4 (SDPP) kDa. Uncharacterized band(s) may appear in some lysates.
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in PC3 cell lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected DDPIV/CD26 in 10 µg of PC3 cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
