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The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5 exons to the first constant exon, which generates transcript variants that encode distinct isoforms
Product Information
Format
Purified
Control
rat brain tissue lysate
Presentation
Purified in PBS with 0.05% NaN3
Quality Level
MQ100
Applications
Application
Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Optimal working dilutions must be determined by the end user.
Biological Information
Immunogen
Gel-purified C5 Cell plectin
Clone
10F6
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Mouse
Specificity
Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Species Reactivity
Rat
Human
Mouse
Species Reactivity Note
Mouse, Rat and Human. Reactivity with other species has not been tested.
Antibody Type
Monoclonal Antibody
Gene Symbol
ACTC1
ACTG1
C14orf49
PLEC1
UniProt Number
P30427
Molecular Weight
300-500 kDa
Product Usage Statements
Quality Assurance
Routinely tested on rat brain tissue lysate
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.