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Millipore Anti-Substance P Rat Ab, 100ul, Monoclonal, Rat
Millipore Anti-Substance P Rat Ab, 100ul, Monoclonal, Rat
List Price$574.56Your Price$574.56
Millipore Detect Substance P Using This Anti-Substance P Antibody, Pain, Clone Nc1 Validated For Use In Ih. - Mill (Additional S&H or Hazmat Fees May Apply)
Detect Substance P using this Anti-Substance P Antibody, pain, clone NC1 validated for use in IH.
Key Applications
Immunohistochemistry
Application Notes
1:100 - 1:200 by immunohistochemistry on human brain.
Optimal working dilutions must be determined by end user.
Biological Information
Immunogen
Substance P conjugated to BSA.
Clone
NC1
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rat
Specificity
Reacts with COOH-terminal end of Substance P. No cross-reactivity to Leu- or Met- enkephalin, somatostatin or beta-endorphin. Eledoisin 5%.
Isotype
IgG2a
Species Reactivity
Human
Mammals
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_003182.1
NM_013996.1
NM_013997.1
NM_013998.1
Entrez Gene Summary
This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Symbol
TAC1
NKNA
Hs.2563
NK2
PPT
NKA
TAC2
Purification Method
Unpurified
UniProt Number
P20366
UniProt Summary
FUNCTION: SwissProt: P20366 # Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. SIZE: 129 amino acids; 15003 Da SUBCELLULAR LOCATION: Secreted. SIMILARITY: SwissProt: P20366 ## Belongs to the tachykinin family.
Product Usage Statements
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100µL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.