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Key Specifications Table
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | FC, IP | M | Purified | Monoclonal Antibody |
| Description | |
|---|---|
| Catalogue Number | MAB2075Z |
| Brand Family | Chemicon® |
| Trade Name |
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| Description | Anti-Integrin β6 Antibody, clone R6G9, azide free |
| Alternate Names |
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| Product Information | |
|---|---|
| Format | Purified |
| Presentation | Sterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives. |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Anti-Integrin β6 Antibody, clone R6G9, azide free is an antibody against Integrin β6 for use in FC & IP. |
| Key Applications |
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| Applications Not Recommended |
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| Application Notes | Flow cytometry Immunoprecipitation: Effective; however because this antibody is an IgG2a, protein G or rabbit anti-mouse IgG is helpful for capture. Immunohistochemistry/immunocytochemistry: The antibody recognizes alphaVbeta6 by immunohistochemistry and immunocytochemistry (acetone fix), but nuclear background staining limits usefulness in these techniques. Then antibody is not function blocking and not effective for western blot. Optimal working dilutions must be determined by end user. |
| Biological Information | |
|---|---|
| Immunogen | Murine NIH 3T3 cells stably transfected with the human (6 subunit |
| Clone | R6G9 |
| Host | Mouse |
| Specificity | Monoclonal antibody MAB2075Z, raised by immunizing Balb/c mice with murine NIH 3T3 cells stably transfected with the human beta6 subunit, recognizes the human beta6 subunit by flow cytometry and is an excellent antibody for immunoprecipitation. |
| Isotype | IgG2a |
| Species Reactivity |
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| Antibody Type | Monoclonal Antibody |
| Entrez Gene Number |
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| Gene Symbol |
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| UniProt Number |
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| UniProt Summary | FUNCTION: SwissProt: P18564 # Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. SIZE: 788 amino acids; 85936 Da SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P18564 ## Belongs to the integrin beta chain family. & Contains 1 VWFA domain. |
| Product Usage Statements | |
|---|---|
| Usage Statement |
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| Storage and Shipping Information | |
|---|---|
| Storage Conditions | Maintain frozen at -20°C in undiluted aliquots for up to 12 months. |
| Packaging Information | |
|---|---|
| Material Size | 100 µg |