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Millipore Tgf- Alpha Protein, Human Recombinant Animal Free
Millipore Tgf- Alpha Protein, Human Recombinant Animal Free
List Price$468.70Your Price$468.70
Millipore Transforming Growth Factor Alpha (Tgf-Α) Is An Egf-Related Polypeptide Growth Factor That Signals Through The Egf Receptor & Stimulates The Proliferation Of A Wide Range Of Epidermal & Epithel - Mill (Additional S&H or Hazmat Fees May Apply)
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue Number
GF313
Description
TGF- α Protein, Human Recombinant Animal Free
Alternate Names
Transforming growth factor alpha
TGFa
TGF alpha
EGF-like TGF
TGF type 1
Background Information
Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Product Information
Formulation
Presentation
Product is filtered through a 0.2 micron filter before lyophilization.
Quality Level
MQ100
Applications
Application
Transforming growth factor alpha (TGF-α) is an EGF-related polypeptide growth factor that signals through the EGF receptor & stimulates the proliferation of a wide range of epidermal & epithelial cells. Manufactured using all non-animal reagents.
Biological Information
Purity
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Source
E. coli
Cross Reactivity
Chicken, Mouse, Rat
Entrez Gene Number
NM_001099691.1
NM_003236.2
UniProt Number
P01135
Product Usage Statements
Quality Assurance
Bioactivity assay: Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store at -20°C for up to 6 months from date of receipt.
