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Millipore The Bone Morphogenetic Protein 4 (Or Bmp-4 Protein) Is A Tgfβ Superfamily Ligand That Is Widely Expressed From Early Embryogenesis Through Adulthood. - Mill (Additional S&H or Hazmat Fees May Apply)
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 97% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue Number
GF167
Description
BMP-4 Protein, Human Recombinant
Alternate Names
BMP4
Bone morphogentic protein-4
DVR-4
Background Information
Bone morphogentic protein 4 (BMP-4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36 kDa homodimeric glycoprotein.
Product Information
Presentation
Product is filtered through a 0.2 micron filter before lyophilization.
Quality Level
MQ100
Applications
Application
The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.
Biological Information
Purity
Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 97% pure by SDS-PAGE gel and HPLC analyses
Source
Hela Cells
Cross Reactivity
None
Entrez Gene Number
NM_001202.3
NM_130850.2
NM_130851.2
UniProt Number
P12644
Product Usage Statements
Quality Assurance
Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store at -20°C for up to 6 months from date of receipt.
