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Millipore Detect Tlsp Receptor Using This Rabbit Polyclonal Antibody, Anti-Tslp Receptor Antibody Validated For Use In Western Blotting, Ihc (Paraffin) & Immunofluorescence. - Mill (Additional S&H or Hazmat Fees May Apply)
Thymic stromal lymphopoietin (TSLP) receptor is a member of the Type I cytokine receptor family (type 5 subfamily). TSLP has been shown to play an important role in dendritic cell maturation and activation. Additionally, TSLP receptor is involved in the positive selection of regulatory T cells, induction of CD4+ T cell-mediated allergic reaction and maintenance of peripheral CD4+ T cell homeostasis. Furthermore, TSLP receptor is implicated in the development of the hematopoietic system. TSLP receptor forms a functional complex with TSLP receptor and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. TSLP receptor is primarily expressed in dendrites and monocytes. Additionally, it is expressed in heart, skeletal muscle, kidney and adult and fetal liver; and weakly expressed in T-cells.
Product Information
Format
Affinity Purified
Control
Human liver tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Detect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Immunofluorescence
Application Notes
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected TSLP receptor in human liver tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human TSLP receptor.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Gene Symbol
CRLF2
Purification Method
Antigen Affinity Purified
UniProt Number
Q9HC73
Molecular Weight
~53 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~27 kDa and ~42 kDa.
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
