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Millipore This Slitrk3 Antibody Is Validated For Use In Wb & Ihc For The Detection Of The Slitrk3 Protein. - Mill (Additional S&H or Hazmat Fees May Apply)
SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
Product Information
Format
Affinity Purified
Control
SK-N-SH cell lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Quality Level
MQ100
Applications
Application
This Slitrk3 antibody is validated for use in WB & IHC for the detection of the Slitrk3 protein.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Immunohistochemistry Analysis: Human brain tissue was prepared using heat-induced epitope retrieval (HIER). Immunostaining was performed using 2.5 µg/mL Slitrk3 antibody.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human Slitrk3.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Species Reactivity
Human
Antibody Type
Polyclonal Antibody
Purification Method
Antigen Affinity Purified
UniProt Number
O94933
Molecular Weight
~120 kDa observed
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in SK-N-SH cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Slitrk3 in 15 µg of SK-N-SH cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
