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Millipore Anti-Prospero Homeobox Protein 1/Prox1 Antibody
Millipore Anti-Prospero Homeobox Protein 1/Prox1 Antibody
List Price$497.28Your Price$497.28
Millipore This Anti-Prospero Homeobox Protein 1/Prox1 Antibody Is Validated For Use In Western Blotting & Ihc For The Detection Of Prospero Homeobox Protein 1/Prox1. - Mill (Additional S&H or Hazmat Fees May Apply)
PROX1 (Prospero homeobox protein 1), the homolog of Drosophila Prospero, is a homeobox-containing transcription factor that binds and functions as a co-receptor of liver receptor homolog 1 (LRH1/NR5A2). It is a specific marker for lymphatic endothelial cells, as well as hepatoblasts and hepatocytes. Human Prox1 shares 97% amino acid sequence identity with mouse and rat Prox1.
Product Information
Format
Affinity Purified
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-Prospero homeobox protein 1/PROX1 Antibody is validated for use in western blotting & IHC for the detection of Prospero homeobox protein 1/PROX1.
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Prospero homeobox protein 1/PROX1 in mouse E16 embryo thalamus tissues (Prof. Samual Pleasure, University of California, San Francisco.).
Alexa Fluor® is a registered trademark of Life Technologies, Inc.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the C-terminus of human Prospero homeobox protein 1/PROX1.
Epitope
C-terminus
Host
Rabbit
Species Reactivity
Rat
Mouse
Species Reactivity Note
Rat and Mouse. Predicted to react with Fish, Human, Chicken, and Bovine based on 100% sequence homology.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_001257545
Gene Symbol
PROX1
Purification Method
Affinity Purfied
UniProt Number
Q92786
Molecular Weight
~95 kDa observed. Uniprot describes a molecular weight at 83 kDa. However, this protein may be observed between 80-110 kDa due to sumoylation and/or alternative start sites (Pan, M. R., et al. (2009). J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011). Genes Cells. 16(11):1063-1070.).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in HEK293 nuclear extract.
Western Blotting Analysis: A 1:500 dilution of this antibody detected Prospero homeobox protein 1/PROX1 in 10 µg of HEK293 nuclear extract.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
