The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Millipore This Anti-Thap11 (Ronin) Antibody Is Validated For Use In Western Blotting, Ihc For The Detection Of Thap11 (Ronin). - Mill (Additional S&H or Hazmat Fees May Apply)
THAP11 (Ronin) is a transcriptional repressor which is predominantly expressed in embryonic stem (ES) cells. It contains a THAP-type zinc finger domain which is characteristic of the THAP 11 family members. In ES cells, THAP11 interacts with the transcriptional co-regulator HCF-1, to recruit chromatin-modifying proteins such as members of the polycomb family of proteins, to induce gene repression. THAP11 targets genes involved in metabolism, transcriptional initiation, and messenger RNA splicing. It plays an important role in maintaining the pluripotent state of ES cells.
Product Information
Format
Affinity Purified
Control
Mouse heart tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level
MQ100
Applications
Application
This Anti-THAP11 (Ronin) Antibody is validated for use in Western Blotting, IHC for the detection of THAP11 (Ronin).
Key Applications
Western Blotting
Immunohistochemistry
Application Notes
Western Blot Analysis: 1 µg/mL from a representative lot detected THAP11 on 10 µg of mouse liver tissue lysate.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected THAP11 in mouse cardiac muscle and mouse liver tissues.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human THAP11.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Species Reactivity
Mouse
Species Reactivity Note
Demonstrated to react with Mouse. Predicted to react with Rat based on 100% sequence homology. Predicted to react with Human based on immunogen design.
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NP_065190
Gene Symbol
THAP11
Purification Method
Affinity Purfied
UniProt Number
Q96EK4
Molecular Weight
~48 kDa observed. Uncharacterized bands appear at ~20-25 kDa in some lysates.
Product Usage Statements
Quality Assurance
Evaluated by Western Blot in mouse heart tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected THAP11 on 10 µg of mouse heart tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
