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Millipore Anti-Bfl-1 Antibody Is A Highly Specific Rabbit Polyclonal Antibody, That Targets Bcl-2-Related Protein A1 & Has Been Tested In Western Blotting, Ihc & Immunofluorescence. - Mill (Additional S&H or Hazmat Fees May Apply)
Protein BFL-1, also known as protein GRS, Bcl-2-like protein 5 (Bcl2-L-5), and Bcl-2-related protein A1 (BCL2A1), is a member of the Bcl-2 family. BFL-1 can interact with Bax and suppress apoptosis by inhibiting the release of cytochrome c and caspase-3 activation. BFL-1 is expressed in peripheral blood, spleen, bone marrow, lung, small intestine, and testis.
Product Information
Format
Affinity Purified
Control
Mouse kidney tissue lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-BFL-1 Antibody is a highly specific rabbit polyclonal antibody, that targets Bcl-2-related protein A1 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
Western Blotting
Immunohistochemistry
Immunofluorescence
Application Notes
Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected BFL-1 in mouse kidney tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected BFL-1 in mouse kidney cells.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human BFL-1.
Epitope
N-terminus
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody recognizes the N-terminus of BFL-1.
Species Reactivity
Mouse
Species Reactivity Note
Demonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody Type
Polyclonal Antibody
Gene Symbol
BCL2A1
BCL2L5
BFL1
GRS
HBPA1
Purification Method
Antigen Affinity Purified
UniProt Number
Q16548
Molecular Weight
~39 kDa observed. Uniprot describes two isoforms at ~19 kDa and ~20 kDa.
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in mouse kidney tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected BFL-1 in 15 µg of mouse kidney tissue lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.