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Millipore Anti-Pd-L2 Antibody Is A Highly Specific Rabbit Polyclonal Antibody, That Targets Programmed Cell Death 1 Ligand 1 & Has Been Tested In Western Blotting, Ihc (Paraffin) & Immunofluorescence. - Mill (Additional S&H or Hazmat Fees May Apply)
Programmed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.
Product Information
Format
Affinity Purified
Control
Raji cell lysate
Presentation
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality Level
MQ100
Applications
Application
Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.
Key Applications
Western Blotting
Immunohistochemistry (Paraffin)
Immunofluorescence
Application Notes
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.
Biological Information
Immunogen
KLH-conjugated linear peptide corresponding to human PD-L2.
Concentration
Please refer to the Certificate of Analysis for the lot-specific concentration.
Host
Rabbit
Specificity
This antibody only recognizes the largest isoform at ~31 kDa.
Species Reactivity
Human
Mouse
Antibody Type
Polyclonal Antibody
Gene Symbol
PDCD1LG2
B7DC
CD273
PDCD1L2
PDL2
Purification Method
Antigen Affinity Purified
UniProt Number
Q9BQ51
Molecular Weight
~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa. Uncharacterized bands may appear in some lysate(s).
Product Usage Statements
Quality Assurance
Evaluated by Western Blotting in Raji cell lysate
Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
