The store will not work correctly when cookies are disabled.
We use cookies to make your experience better.To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Millipore Anti-Phospho-Kdr/Flk-1/Vegfr2 (Tyr1214) Antibody Detects Level Of Phospho-Kdr/Flk-1/Vegfr2 (Tyr1214) & Has Been Published & Validated For Use In Wb. - Mill (Additional S&H or Hazmat Fees May Apply)
0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Quality Level
MQ100
Applications
Application
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1214) Antibody detects level of phospho-KDR/Flk-1/VEGFR2 (Tyr1214) & has been published & validated for use in WB.
Key Applications
Western Blotting
Biological Information
Immunogen
(...FHpYDN...) in which pY corresponds to phosphorylated tyrosine at residue 1214 of human KDR/VEGFR2. Tyr1214 of human KDR corresponds to Tyr1212 in the mouse protein.
Host
Rabbit
Specificity
phospho-KDR/VEGFR2 (Tyr1214)
Isotype
IgG
Species Reactivity
Human
Mouse
Antibody Type
Polyclonal Antibody
Entrez Gene Number
NM_002253
Gene Symbol
KDR
VEGFR-2
VEGFR2
FLK1
VEGFR
CD309
Modifications
Phosphorylation
Purification Method
Protein A Purfied
UniProt Number
P35968
UniProt Summary
FUNCTION: SwissProt: P35968 # Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. SIZE: 1356 amino acids; 151527 Da SUBUNIT: Interacts with SHB upon VEGF activation. Interacts with HIV-1 Tat. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. SIMILARITY: SwissProt: P35968 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
Molecular Weight
200-230 kDa
Product Usage Statements
Quality Assurance
routinely evaluated by immunoblot RIPA lysates from porcine aortic endothelial cells expressing human CSF-1R/murineVEGFR-2 chimera
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
