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Millipore This Anti-Pla2 Antibody, Secretory Is Validated For Use In Elisa, Ih, Wb For The Detection Of Pla2. - Mill (Additional S&H or Hazmat Fees May Apply)
0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Quality Level
MQ100
Applications
Application
This Anti-PLA2 Antibody, secretory is validated for use in ELISA, IH, WB for the detection of PLA2.
Key Applications
ELISA
Immunohistochemistry
Western Blotting
Biological Information
Immunogen
Purified human PLA2; recognizes type II (secretory) PLA2.
Host
Mouse
Specificity
human type II secretory PLA2 in sperm, disc and synovial fluid
Isotype
IgG1κ
Species Reactivity
Human
Antibody Type
Monoclonal Antibody
Entrez Gene Number
NM_000300.2
Gene Symbol
PLA2G2A
sPLA2
PLA2S
PLA2
MOM1
PLA2B
RASF-A
PLAS1
NPS-PLA2
PLA2L
Purification Method
DEAE cellulose chromatography
UniProt Number
P14555
UniProt Summary
FUNCTION: SwissProt: P14555 # Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. COFACTOR: Binds 1 calcium ion per subunit. SIZE: 144 amino acids; 16083 Da SUBCELLULAR LOCATION: Membrane; Peripheral membrane protein. SIMILARITY: SwissProt: P14555 ## Belongs to the phospholipase A2 family. MISCELLANEOUS: Group II phospholipase A2 is found in many cells and also extracellularly. The membrane-bound and secreted forms are identical and are encoded by a single gene.
Molecular Weight
14/18 kDa
Product Usage Statements
Quality Assurance
routinely evaluated on PLA2 under non-reducing conditions
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.