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Millipore Active, N-Terminal Gst-Tagged, Recombinant, Human Ret Amino Acids 658 – End Containing The V804m Mutation. For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804M mutation.
Background Information
The V804M mutation has been identified in patients with familial medullary thyroid carcinoma (FMTC) (Fink et al, (1996), Int. J. Cancer, 69, 312-316; Lesueur F. et al,(2005), JCEM, 90, 3454-3457).
Active, N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804M mutation. For use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
Expressed by baculovirus in Sf21 insect cells.
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
NM_000323
Gene Symbol
RET
CRET
CDHF12
Protein Target
Ret
Purification Method
Glutathione agarose affinity chromatography
Target Sub-Family
TK
UniProt Number
P07949
P35546 (mouse)
Molecular Weight
79.2 kDa
Product Usage Statements
Quality Assurance
Routinely evaluated by phosphorylation of CHKtide.
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
Store -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap. Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
Packaging Information
Material Size
10 µg
Material Package
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-760M when ordering the 250 µg size.
