Sigma-Aldrich Lispher100 Rp18e 10mym Car

Product Name

LiChrospher^®100 RP-18 endcapped (10 µm) LiChroCART^®250-4, suitable for HPLC

Material

stainless steel column

Quality Level

100

Agency

suitable for USP L1

Product Line

LiChrospher^®

Feature

endcapped

Packaging

1 ea of

Extent Of Labeling

21.6% Carbon loading

Parameter

250 bar pressure
60 °C max. temp.

Technique(S)

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

Related Categories

HPLC Columns

General Description

HPLC cartridgeLiChrospher^®RP-18 endcapped is a reliable and versatile traditionally produced spherical silica gel carrier with C-18 endcapped reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds. This sorbent is packed into a LiChroCART 250-4 HPLC cartridge. The connection to the HPLC system is being accomplished by use of the manu-CART NT cartrige holder (1.51486).

Application

• Integration of Solid-Phase Extraction and Reversed-Phase Chromatography in Single Protein-Coated Columns for Direct Injection of Bupivacaine in Human Serum:This study highlights the use of the LiChrosorb^®RP-8 HPLC column in a novel method integrating solid-phase extraction with reversed-phase chromatography. This approach significantly enhances the efficiency and accuracy of bupivacaine analysis in human serum, underscoring the column′s utility in clinical and pharmaceutical settings. The research demonstrates the column′s high performance in complex sample matrices, making it an invaluable tool for analytical chemists and researchers in drug monitoring and pharmacokinetics (Zarad et al., 2020).

Analysis Note

Pressure: ≤ 40 bar
Theoretical Plates (N/m) (Toluene): ≥ 20000
Symmetry (Toluene): 0.8 - 1.4
Capacity factor (Toluene): 1.5 - 3.0LICHROCART is a registered trademark of Merck KGaA, Darmstadt, GermanyLiChrosorb is a registered trademark of Merck KGaA, Darmstadt, GermanyLiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany