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Cell Signaling Myoferlin (E9z4x) Rabbit mAb
List Price
$342.39
Your Price
$342.39
Cell Signaling Myoferlin (E9z4x) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)
NETA PART:
CSIG-99293S
MFG.PART:
99293S
UNSPSC:
12352203
Manufacturer:
Cell Signaling
| Size | 100 µl |
| Reactivity | H |
| Sensitivity | Endogenous |
| Molecular Weight (kDa) | 250 |
| Source/Isotype | Rabbit IgG |
| Application/Dilution | {Western Blotting: 1:1000, Immunofluorescence (Immunocytochemistry): 1:200 - 1:800} |
| Storage | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody. |
| Specificity/Sensitivity | Myoferlin (E9Z4X) Rabbit mAb recognizes endogenous levels of total myoferlin protein. |
| Species Reactivity | Human |
| Source/Purification | Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human myoferlin protein. |
| Background | Myoferlin (MYOF) is a type II transmembrane protein of the ferlin family found mainly in muscle and endothelial cells (1,2). The protein has multiple C2 domains located at its N-terminal cytoplasmic region, which mediate lipid binding and protein-protein interactions (3). Myoferlin is localized to various membrane structures, including the plasma membrane and vesicle membranes, to promote vesicle trafficking (4,5), membrane fusion and repair (6), angiogenesis (7), and adipogenesis (8). High expression of myoferlin has been found in various cancer types and is associated with poor prognosis (3,9). Myoferlin contributes to cancer progression by promoting angiogenesis, vasculogenic mimicry, energy metabolism reprogramming, epithelial-mesenchymal transition, and exosome formation. Inhibition of myoferlin has been proposed as a potential therapeutic treatment for cancer (10-12). |
| SKU | CSIG-99293S |
|---|---|
| Featured | No |
| Supplier Part Number | 99293S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer Name | Cell Signaling |
| MSDS URL | Click here |
| Temperature | -20C |
| CountryOfOrigin | United States |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| ACT Ecolabel | No |