Cell Signaling Cd11c (D3v1e) Xp® Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Cd11c (D3v1e) Xp® Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-93233SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Cd11c (D3v1e) Xp® Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-93233SF

MFG.PART: 93233SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	145
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #45581.
Specificity/Sensitivity	CD11c (D3V1E) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total CD11c protein. This antibody does not cross-react with CD11b.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant human CD11c protein.
Background	CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins (1). CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production (2, 3). CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia (4-7).

Specifications