Cell Signaling Keratin 5 (E2t4b) Rabbit mAb (Ihc Preferred) (Bsa And Azide Free)

Name: Cell Signaling Keratin 5 (E2t4b) Rabbit mAb (Ihc Preferred) (Bsa And Azide Free)
SKU: CSIG-81817SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Keratin 5 (E2t4b) Rabbit mAb (Ihc Preferred) (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-81817SF

MFG.PART: 81817SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M
Sensitivity	Endogenous
Molecular Weight (kDa)	62
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free. For standard formulation of this product see product #71536.
Specificity/Sensitivity	Keratin 5 (E2T4B) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total keratin 5 protein.
Species Reactivity	Human, Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val578 of human keratin 5 protein.
Background	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).

Specifications