Cell Signaling Gata-2 (E8b5c) Rabbit mAb

Name: Cell Signaling Gata-2 (E8b5c) Rabbit mAb
SKU: CSIG-72445S
Price: 406.02 USD

List Price $406.02 Your Price $406.02

Cell Signaling Gata-2 (E8b5c) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-72445S

MFG.PART: 72445S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	51
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:50, Immunohistochemistry (Paraffin): 1:2000 - 1:8000, Immunofluorescence (Immunocytochemistry): 1:800 - 1:1600, Chromatin IP: 1:50, Chromatin IP-seq: 1:50, CUT&RUN: 1:50}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	GATA-2 (E8B5C) Rabbit mAb recognizes endogenous levels of total GATA-2 protein. Non-specific staining was observed in squamous epithelium by immunohistochemistry.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly132 of human GATA-2 protein.
Background	The zinc finger transcription factor GATA-2 is widely expressed and plays an essential role in many developmental processes (1). Studies on GATA-2 knockout mice indicate that this protein is required in hematopoiesis (2). GATA-2 also inhibits the differentiation of white (3) and brown adipocytes (4) and has been shown to suppress the proliferation of neuronal progenitor cells (5).

Specifications