Cell Signaling Ifi6 (E8g9g) Rabbit mAb

Name: Cell Signaling Ifi6 (E8g9g) Rabbit mAb
SKU: CSIG-71578S
Price: 374.71 USD

List Price $374.71 Your Price $374.71

Cell Signaling Ifi6 (E8g9g) Rabbit mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-71578S

MFG.PART: 71578S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	12
Source/Isotype	Rabbit IgG
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	IFI6 (E8G9G) Rabbit mAb recognizes endogenous levels of total IFI6 protein. This antibody does not cross-react with other ISG12 family proteins.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IFI6 protein.
Background	Interferon alpha-inducible protein 6 (IFI6) belongs to the ISG12 family of proteins and is a small, multipass transmembrane protein localized to mitochondrial membranes (1,2). IFI6 is one of the first interferon-stimulated genes to be identified and research studies have shown that IFI6 regulates apoptotic signaling pathways triggered in response to type-I interferons (3,4). In addition, IFI6 participates in type-I interferon-mediated antiviral signaling by mitigating viral replication (5,6).

Specifications