Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Alexa Fluor 647 Conjugate)

Name: Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Alexa Fluor 647 Conjugate)
SKU: CSIG-69310S
Price: 497.93 USD

List Price $497.93 Your Price $497.93

Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Alexa Fluor 647 Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-69310S

MFG.PART: 69310S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl (50 tests)
Reactivity	All
Sensitivity	Transfected Only
Source/Isotype	Rabbit IgG
Application/Dilution	{Flow Cytometry (Live): 1:50}
Storage	Supplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
Specificity/Sensitivity	Whitlow/218 Linker (E3U7Q) Rabbit mAb (Alexa Fluor® 647 Conjugate) recognizes exogenously expressed levels of scFv-based CARs containing a Whitlow/218 linker.
Species Reactivity	All Species Expected
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues of the Whitlow/218 linker peptide.
Background	The Whitlow/218 peptide is a commonly used linker that connects the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The Whitlow/218 linker affords the scFv with enhanced resistance to proteolysis and aggregation (1).

Specifications