Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-66159SF
Price: 912.03 USD

List Price $912.03 Your Price $912.03

Cell Signaling Whitlow/218 Linker (E3u7q) Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-66159SF

MFG.PART: 66159SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	All
Sensitivity	Endogenous
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #57710
Specificity/Sensitivity	Whitlow/218 Linker (E3U7Q) Rabbit mAb (BSA and Azide Free) recognizes exogenously expressed levels of scFv-based CARs containing a Whitlow/218 linker.
Species Reactivity	All Species Expected
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues of the Whitlow/218 linker peptide.
Background	The Whitlow/218 peptide is a commonly used linker that connects the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition. The Whitlow/218 linker affords the scFv with enhanced resistance to proteolysis and aggregation (1).

Specifications