Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific) (Pe Conjugate)

Name: Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific) (Pe Conjugate)
SKU: CSIG-60356S
Price: 454.50 USD

List Price $454.50 Your Price $454.50

Cell Signaling Nanog (D2a3) Xp Rabbit mAb (Mouse Specific) (Pe Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-60356S

MFG.PART: 60356S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl (50 tests)
Reactivity	M
Sensitivity	Endogenous
Source/Isotype	Rabbit IgG
Application/Dilution	{Flow Cytometry (Fixed/Permeabilized): 1:50}
Storage	Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibodies. Protect from light. Do not freeze.
Specificity/Sensitivity	Nanog (D2A3) XP® Rabbit mAb (PE Conjugate) recognizes endogenous levels of total mouse nanog protein. This antibody is expected to recognize nanog 1a and 1b isoforms. This antibody does not cross-react with human nanog.
Species Reactivity	Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of mouse nanog protein.
Background	Nanog is a homeodomain-containing transcription factor that is essential for the maintenance of pluripotency and self renewal in embryonic stem cells (1). Nanog expression is controlled by a network of factors including Sox2 and the key pluripotency regulator Oct-4 (1). Recent advances in somatic cell reprogramming have utilized viral expression of combinations of transcription factors including nanog, Oct-4, Sox2, KLF4, c-Myc, and LIN28 (2,3).

Specifications