Cell Signaling T-Bet/Tbx21 (E4i2k) Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling T-Bet/Tbx21 (E4i2k) Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-53753SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling T-Bet/Tbx21 (E4i2k) Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-53753SF

MFG.PART: 53753SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M
Sensitivity	Endogenous
Molecular Weight (kDa)	62
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide free. For standard formulation of this product see product #97135.
Specificity/Sensitivity	T-bet/TBX21 (E4I2K) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total T-bet/TBX21 protein. Reactivity for IHC-P is mouse only. E412K non-specifically labels the submucosa and external muscularis of mouse colon by immunofluorescence.
Species Reactivity	Human, Mouse
Source/Purification	Monoclonal antibody is produced by immunizing animals with a recombinant protein fragment derived from mouse T-bet/TBX21 protein.
Background	The T-box gene family consists of transcription factors characterized by a related DNA-binding domain (T-box) of approximately 200 amino acids (1,2). The T-box genes exhibit diverse temporal and spatial patterns in the developing embryo. Studies have demonstrated members of this family play crucial roles during embryogenesis in a wide range of organisms by regulating cell fate decisions to establish the early body plan and to regulate later processes underlying organogenesis (3-5). Mutations in T-box genes are associated with many developmental defects (6). Recent studies also indicate potential roles in cancer by members of the T-box family (7-9).

Specifications