Cell Signaling Keratin 8/18 (C51) Mouse mAb (Bsa And Azide Free)

Name: Cell Signaling Keratin 8/18 (C51) Mouse mAb (Bsa And Azide Free)
SKU: CSIG-51274SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Keratin 8/18 (C51) Mouse mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-51274SF

MFG.PART: 51274SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	46 Keratin 18. 55 Keratin 8.
Source/Isotype	Mouse IgG1
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #4546.
Specificity/Sensitivity	Keratin 8/18 (C51) Mouse mAb (BSA and Azide Free) detects endogenous levels of total keratins 8 and 18. The antibody does not cross-react with other keratins.
Species Reactivity	Human, Monkey
Source/Purification	Monoclonal antibody (isotype: IgG1) is produced by immunizing a BALB/c mouse with a cytoskeleton preparation from HeLa cells.
Background	Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).

Specifications