Cell Signaling Pomc (Ah26) Mouse mAb

Name: Cell Signaling Pomc (Ah26) Mouse mAb
SKU: CSIG-47193S
Price: 353.50 USD

List Price $353.50 Your Price $353.50

Cell Signaling Pomc (Ah26) Mouse mAb - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-47193S

MFG.PART: 47193S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Source/Isotype	Mouse IgG1 kappa
Application/Dilution	{Immunohistochemistry (Paraffin): 1:800 - 1:3200}
Storage	Supplied in 10 mM PBS containing 0.05% BSA and 0.05% sodium azide. Stable for 36 months when stored at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present, but will not interfere with antibody performance.
Specificity/Sensitivity	POMC (AH26) Mouse mAb recognizes endogenous levels of total POMC protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino acids 1-24 of human POMC protein.
Background	Pro-opiomelanocortin (POMC) is a precursor protein expressed in the pituitary and the brain where it is processed into several peptide hormones and neuropeptides. Among these peptides are ACTH, α- and β-MSH, β-and γ-LPH, CLIP, β-endorphin, and N-POMC (1). POMC is involved in hypothalamic circuits regulating feeding behavior and POMC-producing neurons promote satiety (2). POMC neurons are also the target of leptin and insulin for the promotion of the browning of white fat (3).

Specifications