Cell Signaling Calbindin (D1i4q) Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Calbindin (D1i4q) Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-46343SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Calbindin (D1i4q) Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-46343SF

MFG.PART: 46343SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	28
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free. For standard formulation of this product see product #13176.
Specificity/Sensitivity	Calbindin (D1I4Q) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total calbindin protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human calbindin protein.
Background	Calcium-binding proteins of different subfamilies regulate the second messenger calcium. Calbindin, calmodulin, S-100, parvalbumin, and troponin C are members of the low molecular weight calcium-binding protein family (1). Calbindin is expressed in discrete neuronal populations within the CNS and is thought to act as an intracellular calcium buffering protein. Most Purkinje cells express calbindin, which is expressed when neurons start to migrate and differentiate. In contrast, other calcium buffering proteins, such as parvalbumin, are expressed later during development and in parallel with increasing neuronal activity (2).

Specifications