Cell Signaling Hnrnp A0 Antibody

Name: Cell Signaling Hnrnp A0 Antibody
SKU: CSIG-4046S
Price: 309.06 USD

List Price $309.06 Your Price $309.06

Cell Signaling Hnrnp A0 Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-4046S

MFG.PART: 4046S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	32, 34
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:100, Immunofluorescence (Immunocytochemistry): 1:100}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	hnRNP A0 Antibody detects endogenous levels of total hnRNP A0 protein. This antibody cross-reacts with hnRNP A2/B1 protein.
Species Reactivity	Human, Mouse, Rat, Monkey
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human hnRNP A0. Antibodies are purified by protein A and peptide affinity chromatography.
Background	Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism, and transport of nuclear pre-mRNA transcripts (1). The A/B subfamily of hnRNP includes A1, A2/B1, A3, and A0. hnRNP A0 is phosphorylated at Ser84 by MAPKAPK-2 in response to LPS treatment in mouse macrophage cells, which might play a key role in stimulating translation of the TNF-α message (2).

Specifications