Cell Signaling Ki-67 (D3b5) Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Ki-67 (D3b5) Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-34330SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Ki-67 (D3b5) Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-34330SF

MFG.PART: 34330SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	359
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #9129
Specificity/Sensitivity	Ki-67 (D3B5) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total Ki-67 protein. Species reactivity for IHC-P is mouse only.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Monoclonal antibody is produced by immunizing animals with a recombinant protein fragment corresponding to residues near the central region of human Ki-67 protein.
Background	Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).

Specifications