Cell Signaling Cd141/Thrombomodulin (E7y9p) Xp® Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling Cd141/Thrombomodulin (E7y9p) Xp® Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-34149SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling Cd141/Thrombomodulin (E7y9p) Xp® Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-34149SF

MFG.PART: 34149SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	90
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #43514.
Specificity/Sensitivity	Thrombomodulin (E7Y9P) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total CD141/Thrombomodulin protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with human CD141/Thrombomodulin recombinant protein.
Background	CD141/Thrombomodulin (TM, THBD, BDCA-3) is an integral membrane protein expressed on the surface of endothelial cells (1). Acting as a cofactor with Thrombin, CD141/Thrombomodulin activates and initiates the Protein C anticoagulant pathway (1-2). CD141/Thrombomodulin is expressed by a small subset of human CD11c+ myeloid dendritic cells (3-4). These CD141+XCR1+ dendritic cells cross-present antigens to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells (3-5).

Specifications