Cell Signaling Hspa4/Apg-2 Antibody

Name: Cell Signaling Hspa4/Apg-2 Antibody
SKU: CSIG-3303S
Price: 309.06 USD

List Price $309.06 Your Price $309.06

Cell Signaling Hspa4/Apg-2 Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-3303S

MFG.PART: 3303S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	110
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	HSPA4/Apg-2 Antibody detects endogenous levels of total HSPA4 protein.
Species Reactivity	Human, Mouse, Rat, Monkey
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to human HSPA4. Antibodies are purified by protein A and peptide affinity chromatography.
Background	The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins (1). Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions (2). Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress (3,4).

Specifications