Cell Signaling Hexokinase I Antibody

Name: Cell Signaling Hexokinase I Antibody
SKU: CSIG-2804S
Price: 309.06 USD

List Price $309.06 Your Price $309.06

Cell Signaling Hexokinase I Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-2804S

MFG.PART: 2804S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H Mk
Sensitivity	Endogenous
Molecular Weight (kDa)	102
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	Hexokinase I Antibody detects endogenous levels of total hexokinase I protein.
Species Reactivity	Human, Monkey
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human hexokinase I. Antibodies are purified by peptide affinity chromatography.
Background	Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).

Specifications