Cell Signaling T-Bet/Tbx21 (D6n8b) Xp® Rabbit mAb (Bsa And Azide Free)

Name: Cell Signaling T-Bet/Tbx21 (D6n8b) Xp® Rabbit mAb (Bsa And Azide Free)
SKU: CSIG-27112SF
Price: 851.43 USD

List Price $851.43 Your Price $851.43

Cell Signaling T-Bet/Tbx21 (D6n8b) Xp® Rabbit mAb (Bsa And Azide Free) - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-27112SF

MFG.PART: 27112SF

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µg
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	58-68
Source/Isotype	Rabbit IgG
Application/Dilution	{}
Storage	Supplied in 1X PBS, BSA and Azide Free.For standard formulation of this product see product #13232.
Specificity/Sensitivity	T-bet/TBX21 (D6N8B) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total T-bet/TBX21 protein.
Species Reactivity	Human
Source/Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly465 of human T-bet/TBX21 protein.
Background	The T-box gene family consists of transcription factors characterized by a related DNA-binding domain (T-box) of approximately 200 amino acids (1,2). The T-box genes exhibit diverse temporal and spatial patterns in the developing embryo. Studies have demonstrated members of this family play crucial roles during embryogenesis in a wide range of organisms by regulating cell fate decisions to establish the early body plan and to regulate later processes underlying organogenesis (3-5). Mutations in T-box genes are associated with many developmental defects (6). Recent studies also indicate potential roles in cancer by members of the T-box family (7-9).

Specifications