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Cell Signaling Cd161/Klrb1 (Hp-3g10) Mouse mAb (Percp-Cy5.5 Conjugate)
List Price
$360.57
Your Price
$360.57
Cell Signaling Cd161/Klrb1 (Hp-3g10) Mouse mAb (Percp-Cy5.5 Conjugate) - CSIG (Additional S&H or Hazmat Fees May Apply)
NETA PART:
CSIG-26217S
MFG.PART:
26217S
UNSPSC:
12352203
Manufacturer:
Cell Signaling
| Size | 500 µl (100 tests) |
| Reactivity | H |
| Sensitivity | Endogenous |
| Source/Isotype | Mouse IgG1 kappa |
| Application/Dilution | {Flow Cytometry (Live): 1:20} |
| Storage | Supplied in 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2. This product is stable for 6 months when stored at 4ºC. Do not aliquot the antibody. Protect from light. Do not freeze. |
| Specificity/Sensitivity | CD161/KLRB1 (HP-3G10) Mouse mAb (PerCP-Cy5.5® Conjugate) recognizes endogenous levels of total CD161/KLRB1 protein. This antibody detects an epitope within the extracellular domain. |
| Species Reactivity | Human |
| Source/Purification | This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. |
| Background | CD161/KLRB1 (Killer cell lectin-like receptor subfamily B member 1, also known as CLEC5B and NKR-P1A) is a type II transmembrane protein that is expressed on the majority of Natural Killer (NK) cells, NK T cells, and some T lymphocytes (1). CD161/KLRB1 is also expressed on Th17 cells, promotes their generation, and modulates their function (2). Engagement with its ligand lectin-like transcript 1 (LLT1) inhibits NK cell function, while LLT1 and CD161/KLRB1 interaction in the presence of a TCR signal enhances IFN-gamma production by T cells (3,4). There are several different CD161 isoforms in rodents and some function as activating receptors as well (5,6).This HP-3G10 antibody is used for flow cytometric analysis of CD161/KLRB1 expression on NK, NKT, and various subsets of T cells. |
| SKU | CSIG-26217S |
|---|---|
| Featured | No |
| Supplier Part Number | 26217S |
| UM | EA |
| UNSPSC | 12352203 |
| Manufacturer Name | Cell Signaling |
| MSDS URL | Click here |
| Temperature | +4C |
| CountryOfOrigin | United States |
| ProductLine | CSIG |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 8.000000 |
| Lead Time | 5 |
| Hazardous | N |
| ACT Ecolabel | No |