Cell Signaling Alpha-Smooth Muscle Actin Antibody

Name: Cell Signaling Alpha-Smooth Muscle Actin Antibody
SKU: CSIG-14968S
Price: 309.06 USD

List Price $309.06 Your Price $309.06

Cell Signaling Alpha-Smooth Muscle Actin Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-14968S

MFG.PART: 14968S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H M R
Sensitivity	Endogenous
Molecular Weight (kDa)	42
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	α-Smooth Muscle Actin Antibody recognizes endogenous levels of total α-smooth muscle actin protein.
Species Reactivity	Human, Mouse, Rat
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human α-smooth muscle actin protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background	Actin proteins are major components of the eukaryotic cytoskeleton. At least six vertebrate actin isoforms have been identified. The cytoplasmic β- and γ-actin proteins are referred to as “non-muscle” actin proteins as they are predominantly expressed in non-muscle cells where they control cell structure and motility (1). The α-cardiac and α-skeletal actin proteins are expressed in striated cardiac and skeletal muscles, respectively. The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle, respectively. The α-smooth muscle actin (ACTA2) is also known as aortic smooth muscle actin. These actin isoforms regulate the contractile potential of muscle cells (1).

Specifications