Cell Signaling Dock2 Antibody

Name: Cell Signaling Dock2 Antibody
SKU: CSIG-10127S
Price: 309.06 USD

List Price $309.06 Your Price $309.06

Cell Signaling Dock2 Antibody - CSIG (Additional S&H or Hazmat Fees May Apply)

NETA PART: CSIG-10127S

MFG.PART: 10127S

UNSPSC: 12352203

Manufacturer: Cell Signaling

Description

Size	100 µl
Reactivity	H
Sensitivity	Endogenous
Molecular Weight (kDa)	200
Source/Isotype	Rabbit
Application/Dilution	{Western Blotting: 1:1000, Immunoprecipitation: 1:100}
Storage	Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
Specificity/Sensitivity	DOCK2 Antibody recognizes endogenous levels of total DOCK2 protein.
Species Reactivity	Human
Source/Purification	Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human DOCK2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background	DOCK2 (dedicator of cytokinesis 2) is a member of the DOCK-A subfamily of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins (1,3). Expressed in leukocytes, DOCK2 activates isoforms of Rac which regulate chemotaxis as part of the immune response (1,2,4).

Specifications