We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Vv116; 5 Mg; 2647442-33-7; ≥95%
List Price
$474.00
Your Price
$474.00
Cayman Vv116; 5 Mg; 2647442-33-7; ≥95% - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-37745-5
MFG.PART:
37745-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
UK 5099 is a potent inhibitor of the mitochondrial pyruvate carrier (MPC) that inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50 = 50 nM). It decreases glucose flux to the TCA cycle and increases production of M6 citrate via glutaminolytic flux through malic enzymes without affecting ATP-linked or uncoupled oxygen consumption in C2C12 myotubes when used at a concentration of 10 mM. UK 5099 decreases ATP-linked and uncoupled oxygen consumption in C2C12 myotubes when used in combination with BPTES (Item No. ) and/or etomoxir (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-cyano-3-(1-
CAS Number
56396-35-1
Molecular Formula
C18H12N2O2
Formula Weight
288.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 15 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 5 mg/ml
λmax
210, 250, 383 nm
SMILES
O=C(/C(C#N)=C/C(C1=C2C=CC=C1)=CN2C3=CC=CC=C3)O
InChi Code
InChI=1S/C18H12N2O2/c19-11-13(18(21)22)10-14-12-20(15-6-2-1-3-7-15)17-9-5-4-8-16(14)17/h1-10,12H,(H,21,22)/b13-10+
InChi Key
BIZNHCWFGNKBBZ-JLHYYAGUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-37745-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 37745-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 2647442-33-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |