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Cayman Gap 27 (Trifluoroacetate Salt), 5mg
List Price
$469.00
Your Price
$469.00
Cayman Gap 27 (Trifluoroacetate Salt), 5mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-35124-5
MFG.PART:
35124-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Quinidine-d3 is intended for use as an internal standard for the quantification of quinidine (Item No. ) by GC- or LC-MS. Quinidine is a stereoisomer of the antimalarial agent quinine (Item No. ) and a class Ia antiarrhythmic agent., Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent manner. It decreases the amplitude and duration of action potentials in isolated canine ventricular myocytes. Quinidine inhibits KKr, peak INa, and late INa (IC50s = 4.5, 11, and 12 µM, respectively) and can induce torsade de pointes in isolated rabbit hearts when used at a concentration of 1 µM. It induces QT prolongation in dogs. Quinidine also binds to M2 muscarinic acetylcholine receptors (Ki = 7.5 µM for human recombinant receptors expressed in HM2-B10 cells). Formulations containing quinidine have been used in the treatment of atrial fibrillation and ventricular arrhythmias.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6′-(methoxy-
CAS Number
1267657-68-0
Synonyms
- (+)-Quinidine-d3
- β-Quinidine-d3
Molecular Formula
C20H21D3N2O2
Formula Weight
327.4
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- Chloroform: slightly soluble
- Methanol: slightly, heated
SMILES
C=C[C@@H](C[N@@]1CC2)[C@@H]2C[C@]1([H])[C@@H](O)C3=CC=NC4=CC=C(OC([2H])([2H])[2H])C=C43
InChi Code
InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19+,20-/m0/s1/i2D3
InChi Key
LOUPRKONTZGTKE-QMROFPFZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-35124-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 35124-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |